Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50008152
TargetHistone deacetylase 1(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant full length HDAC1 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 27nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant full length human HDAC2 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 56nMAssay Description:Inhibition of recombinant full length HDAC6 (unknown origin) using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 102nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged human HDAC10 (2 to 631 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 392nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 441nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 473nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 682nMAssay Description:Inhibition of recombinant full length C-terminal His-tagged human HDAC8 expressed in baculovirus infected in Sf9 cells using Ac-peptide-AMC as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 11(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC4 expressed in sf9 insect cells using Ac-peptide-AMC as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50516203(CHEMBL4517151)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate after 1 hr by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in Sf9 cells using Ac-peptide-AMC as substrate after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 5(Human)
Sichuan University and Collaborative Innovation Center of Biotherapy

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human HDAC5 expressed in baculovirus infected Sf9 cells using Ac-peptide-AMC as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed