Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50008150
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM4994(CHEMBL674 | (3R,4R,5S)-5-amino-4-acetamido-3-(pent...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516174(CHEMBL4448599)
Affinity DataIC50: 44nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM4994(CHEMBL674 | (3R,4R,5S)-5-amino-4-acetamido-3-(pent...)
Affinity DataIC50: 67nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516189(CHEMBL4443707)
Affinity DataIC50: 210nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516183(CHEMBL4519625)
Affinity DataIC50: 940nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516191(CHEMBL4563229)
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516175(CHEMBL4543729)
Affinity DataIC50: 3.07E+3nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516190(CHEMBL4447730)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516188(CHEMBL4583873)
Affinity DataIC50: 8.33E+3nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516174(CHEMBL4448599)
Affinity DataIC50: 8.34E+3nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516187(CHEMBL4475915)
Affinity DataIC50: 8.38E+3nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516180(CHEMBL4540568)
Affinity DataIC50: 9.34E+3nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516186(CHEMBL4562953)
Affinity DataIC50: 1.33E+4nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516190(CHEMBL4447730)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516177(CHEMBL4474055)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516178(CHEMBL4563489)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516185(CHEMBL4557580)
Affinity DataIC50: 2.74E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516183(CHEMBL4519625)
Affinity DataIC50: 3.18E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516179(CHEMBL4445358)
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516186(CHEMBL4562953)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516177(CHEMBL4474055)
Affinity DataIC50: 4.84E+4nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516191(CHEMBL4563229)
Affinity DataIC50: 5.66E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516181(CHEMBL4535834)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516192(CHEMBL4455023)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516185(CHEMBL4557580)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516173(CHEMBL4591575)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516175(CHEMBL4543729)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516172(CHEMBL4520501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516180(CHEMBL4540568)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516192(CHEMBL4455023)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516189(CHEMBL4443707)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516187(CHEMBL4475915)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516184(CHEMBL4591611)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516182(CHEMBL4464207)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516172(CHEMBL4520501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516181(CHEMBL4535834)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516179(CHEMBL4445358)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516178(CHEMBL4563489)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516188(CHEMBL4583873)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516176(CHEMBL4463961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516184(CHEMBL4591611)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516182(CHEMBL4464207)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516176(CHEMBL4463961)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/goose/Guangdong/SH7/2013(H5N1)) Neuraminidase N1 by using 4-MUNANA as substrate preincubated for 10 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus (strain A/Memphis/1/1971 H3N2))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50516173(CHEMBL4591575)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of influenza A virus (A/Chicken/Hebei/LZF/2014(H5N2)) Neuraminidase N2 in using 4-MUNANA as substrate preincubated for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed