Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50009074
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525178(CHEMBL4437852)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525180(CHEMBL4446236)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525181(CHEMBL4437865)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525179(CHEMBL4450474)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525180(CHEMBL4446236)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525181(CHEMBL4437865)
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525179(CHEMBL4450474)
Affinity DataIC50: 144nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525180(CHEMBL4446236)
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525179(CHEMBL4450474)
Affinity DataIC50: 215nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 234nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525178(CHEMBL4437852)
Affinity DataIC50: 274nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 310nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525181(CHEMBL4437865)
Affinity DataIC50: 381nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525178(CHEMBL4437852)
Affinity DataIC50: 441nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 900nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 1.67E+3nMAssay Description:Inhibition of recombinant human His tagged HDAC1 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525178(CHEMBL4437852)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 7.23E+3nMAssay Description:Inhibition of recombinant human His tagged HDAC6 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525181(CHEMBL4437865)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetNuclear receptor corepressor 1(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC3/NCOR1 assessed as decrease in deacetylation of FLUOR DE LYS SIRT1 substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525178(CHEMBL4437852)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human His tagged HDAC6 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525179(CHEMBL4450474)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525180(CHEMBL4446236)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human His tagged HDAC6 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525180(CHEMBL4446236)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525179(CHEMBL4450474)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human His tagged HDAC6 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50242817(CHEMBL4087968 | US20240150300, Compound Chidamide)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525179(CHEMBL4450474)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525178(CHEMBL4437852)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525180(CHEMBL4446236)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM19422(N-acetyldinaline | N-(2-aminophenyl)-4-acetamidobe...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human His tagged HDAC6 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525181(CHEMBL4437865)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human HDAC8 assessed as decrease in deacetylation of FLUOR DE LYS substrate preincubated for 10 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Beijing University of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50525181(CHEMBL4437865)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant human His tagged HDAC6 expressed in baculovirus infected insect cells assessed as decrease in deacetylation of FLUOR DE LYS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed