Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50002440
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(CL-277082 | 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dime...)
Affinity DataIC50: 140nMAssay Description:Compound was evaluated for the effect on Cholesterol O-Acyltransferase (ACAT) in intestinal microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(CL-277082 | 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dime...)
Affinity DataIC50: 740nMAssay Description:Compound was evaluated for the effect on Cholesterol O-Acyltransferase (ACAT) in intestinal microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(CL-277082 | 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dime...)
Affinity DataIC50: 810nMAssay Description:Inhibition of smooth muscle cell ACAT activity for cells stimulated by cationized LDL.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(CL-277082 | 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dime...)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of smooth muscle cell ACAT activity for cells stimulated by native LDL.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50022279(CL-277082 | 3-(2,4-Difluoro-phenyl)-1-[4-(2,2-dime...)
Affinity DataIC50: 6.06E+3nMAssay Description:Compound was evaluated for the effect on Cholesterol O-Acyltransferase (ACAT) in Aorta (homogenate Low-density lipoproteins (LDL)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSterol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 1.70E+4nMAssay Description:In vitro inhibitory activity against acyl coenzyme A:cholesterol acyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed