Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50008723
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521692(CHEMBL4441013)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521699(CHEMBL4572376)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521689(CHEMBL4436202)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521691(CHEMBL4587441)
Affinity DataIC50: 14nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521690(CHEMBL4520052)
Affinity DataIC50: 20nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521687(CHEMBL4560735)
Affinity DataIC50: 33nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521697(CHEMBL4468174)
Affinity DataIC50: 33nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521698(CHEMBL4555612)
Affinity DataIC50: 35nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521678(CHEMBL4521151)
Affinity DataIC50: 38nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50438848(CHEMBL2420480)
Affinity DataIC50: 41nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50438864(CHEMBL2420507)
Affinity DataIC50: 42nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521701(CHEMBL4457155)
Affinity DataIC50: 65nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521688(CHEMBL4546104)
Affinity DataIC50: 70nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521702(CHEMBL4518508)
Affinity DataIC50: 130nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50438863(CHEMBL2420465 | 10-(4-Hydroxyphenyl)-2,4-dioxo-pyr...)
Affinity DataIC50: 140nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521683(CHEMBL4576353)
Affinity DataIC50: 150nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521686(CHEMBL4557001)
Affinity DataIC50: 190nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521681(CHEMBL4464179)
Affinity DataIC50: 200nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521693(CHEMBL4471861)
Affinity DataIC50: 270nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521703(CHEMBL4536546)
Affinity DataIC50: 300nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521680(CHEMBL4444838)
Affinity DataIC50: 320nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521677(CHEMBL4590491)
Affinity DataIC50: 380nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50438865(CHEMBL2420506 | 2,4-Dioxo-10-phenyl-pyrimido[4,5-b...)
Affinity DataIC50: 640nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521679(CHEMBL4470162)
Affinity DataIC50: 880nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521696(CHEMBL4585923)
Affinity DataIC50: 930nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521694(CHEMBL4470609)
Affinity DataIC50: 960nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521695(CHEMBL4473892)
Affinity DataIC50: 990nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521700(CHEMBL4449643)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521704(CHEMBL4585941)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521682(CHEMBL4473717)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521705(CHEMBL4581905)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521676(CHEMBL4525013)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521685(CHEMBL4469686)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 2(Human)
National Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50521684(CHEMBL4434664)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed