Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50004195
TargetLymphocyte antigen 96(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataKd:  1.85E+5nMAssay Description:Binding affinity to recombinant human 10His-tagged MD2 (Glu17 to Asn160 residues) expressed in Escherichia coli by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetToll-like receptor 4(Human)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataKd:  1.46E+5nMAssay Description:Binding affinity to recombinant human C-terminal 10His-tagged TLR4 (Glu24 to Lys631 residues) expressed in mouse NS0 cells by surface plasmon resonan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataIC50: 530nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96/Toll-like receptor 4(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501802(CHEMBL4544533)
Affinity DataIC50: 730nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501803(CHEMBL4458502)
Affinity DataIC50: 840nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501804(CHEMBL4517719)
Affinity DataIC50: 890nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501805(CHEMBL4468247)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501805(CHEMBL4468247)
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501802(CHEMBL4544533)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetLymphocyte antigen 96(Mouse)
Wenzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50501803(CHEMBL4458502)
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced TNFalpha production prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed