Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50022618
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431867(US10550114, Compound 1a)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50637405(Capivasertib | Azd 5363 | Azd-5363 | AZC5363 | AZD...)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653017(CHEMBL5712063)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431882(US10550114, Compound 46)
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50398379(CHEMBL2177390 | US10550114, Compound GDC-0068 | US...)
Affinity DataIC50: 3.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431877(US10550114, Compound 32)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653019(CHEMBL5712046)
Affinity DataIC50: 3.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431875(US10550114, Compound 30)
Affinity DataIC50: 9.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50313650(8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]tr...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431885(US10550114, Compound 49)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653020(CHEMBL5712066)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431881(US10550114, Compound 36)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653018(CHEMBL5712044)
Affinity DataIC50: 53nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653021(CHEMBL5712058)
Affinity DataIC50: 126nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653022(CHEMBL5712059)
Affinity DataIC50: 192nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431886(US10550114, Compound 50)
Affinity DataIC50: 285nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431867(US10550114, Compound 1a)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653017(CHEMBL5712063)
Affinity DataKi:  4.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431877(US10550114, Compound 32)
Affinity DataKi:  6.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653019(CHEMBL5712046)
Affinity DataKi:  7.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431882(US10550114, Compound 46)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431875(US10550114, Compound 30)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431885(US10550114, Compound 49)
Affinity DataKi:  27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431881(US10550114, Compound 36)
Affinity DataKi:  33nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653020(CHEMBL5712066)
Affinity DataKi:  39nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653021(CHEMBL5712058)
Affinity DataKi:  67nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653018(CHEMBL5712044)
Affinity DataKi:  99nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50653022(CHEMBL5712059)
Affinity DataKi:  327nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM431886(US10550114, Compound 50)
Affinity DataKi:  362nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed