Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50008991
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524293(CHEMBL4542285)
Affinity DataIC50: 14nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524293(CHEMBL4542285)
Affinity DataIC50: 16nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524292(CHEMBL4521504)
Affinity DataIC50: 18nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524292(CHEMBL4521504)
Affinity DataIC50: 23nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 44nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50035696(AMD-3100 | CHEMBL18442 | 11-{4-[4,8, 11-1,4,8,11te...)
Affinity DataIC50: 51nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524291(CHEMBL4469971)
Affinity DataIC50: 147nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524291(CHEMBL4469971)
Affinity DataIC50: 147nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524295(CHEMBL4441528)
Affinity DataIC50: 193nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524295(CHEMBL4441528)
Affinity DataIC50: 193nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524297(CHEMBL4565225)
Affinity DataIC50: 474nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524290(CHEMBL4526799)
Affinity DataIC50: 615nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524290(CHEMBL4526799)
Affinity DataIC50: 1.10E+3nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524293(CHEMBL4542285)
Affinity DataIC50: 2.87E+3nMAssay Description:Antagonist activity at CXCR4 receptor in human SupT1 cells assessed as inhibition of SDF-1alpha-induced chemotaxis at preincubated for 2 hrs followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524292(CHEMBL4521504)
Affinity DataIC50: 4.03E+3nMAssay Description:Antagonist activity at CXCR4 receptor in human SupT1 cells assessed as inhibition of SDF-1alpha-induced chemotaxis at preincubated for 2 hrs followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524294(CHEMBL4444790)
Affinity DataIC50: 7.42E+3nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524294(CHEMBL4444790)
Affinity DataIC50: 9.12E+3nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524296(CHEMBL4453409)
Affinity DataIC50: 5.00E+4nMAssay Description:Competitive binding affinity to CXCR4 in human SupT1 cells incubated for 40 mins by 12G5 antibody based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 4(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50524296(CHEMBL4453409)
Affinity DataIC50: 5.00E+4nMAssay Description:Competitive binding affinity to CXCR4 receptor (unknown origin) expressed in CHO cells incubated for 40 mins by 12G5 antibody based fluorescence anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed