Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50007748
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50512267(CHEMBL4471571)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50512265(CHEMBL4587135)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50334594(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)p...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50512263(CHEMBL4580829)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50512266(CHEMBL4461676)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50512268(CHEMBL4444509)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
The First Affiliated Hospital of Dalian Medical University

Curated by ChEMBL
LigandPNGBDBM50512264(CHEMBL4452825)
Affinity DataIC50: 76nMAssay Description:Inhibition of human recombinant N-terminal His-tagged FAK (393 to 698 residues) expressed in baculovirus infected Sf9 insect cells using Poly (4:1 Gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed