Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50008924
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523669(CHEMBL4535169)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 6nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523672(CHEMBL4440218)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 8nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523673(CHEMBL4589873)
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523670(CHEMBL4467333)
Affinity DataIC50: 11nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523674(CHEMBL4536349)
Affinity DataIC50: 18nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523665(CHEMBL4542493)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523666(CHEMBL4462149)
Affinity DataIC50: 28nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523671(CHEMBL4563971)
Affinity DataIC50: 29nMAssay Description:Inhibition of human PI3Kdelta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 38nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 42nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 79nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 92nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: 112nMAssay Description:Inhibition of human PI3Kgamma using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 241nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 289nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 342nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 421nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 571nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523668(CHEMBL4550603)
Affinity DataIC50: 580nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: 589nMAssay Description:Inhibition of human PI3Kbeta using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523664(CHEMBL4454741)
Affinity DataIC50: 676nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 831nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: 891nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50403068(CHEMBL2216870 | IDELALISIB | US9745321, CAL-101)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mTOR (unknown origin) assessed as reduction in p70S6K phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50523667(CHEMBL4560054)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed