Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50009049
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524871(CHEMBL4524329)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524864(CHEMBL4566670)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 55nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 expressed in baculovirus infected BTI-TN-5B1-4 insect cells using Met-Pro-pNA as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524844(CHEMBL4438796)
Affinity DataIC50: 57nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524868(CHEMBL4552396)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524861(CHEMBL4536649)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524860(CHEMBL4460784)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524853(CHEMBL4462995)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524862(CHEMBL4475680)
Affinity DataIC50: 74nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524841(CHEMBL4558399)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524870(CHEMBL4464652)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524859(CHEMBL4466601)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524842(CHEMBL4469817)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524869(CHEMBL4465025)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524856(CHEMBL4546986)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM17594(N'-[(2S,3R)-3-amino-2-hydroxy-5-(propan-2-ylsulfan...)
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human MetAP2 using Met-Ala-Ser as substrate measured at 20 secs interval for 20 mins by AAO/horse radish peroxidase enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524858(CHEMBL4559822)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524840(CHEMBL4441859)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524851(CHEMBL4584721)
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524862(CHEMBL4475680)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and cobalt as co-facor preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524848(CHEMBL4441472)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524863(CHEMBL4463329)
Affinity DataIC50: 220nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524849(CHEMBL4549484)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524872(CHEMBL4589384)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524867(CHEMBL4556036)
Affinity DataIC50: 280nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524845(CHEMBL4447796)
Affinity DataIC50: 380nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524865(CHEMBL4543409)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524866(CHEMBL4464827)
Affinity DataIC50: 440nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524847(CHEMBL4469283)
Affinity DataIC50: 480nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524873(CHEMBL4576078)
Affinity DataIC50: 540nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524852(CHEMBL4587873)
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524854(CHEMBL4444678)
Affinity DataIC50: 590nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524855(CHEMBL4545625)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524846(CHEMBL4563305)
Affinity DataIC50: 740nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524857(CHEMBL4529723)
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524850(CHEMBL4556838)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetMethionine aminopeptidase 2(Human)
Merck Healthcare

Curated by ChEMBL
LigandPNGBDBM50524843(CHEMBL4572185)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged MetAP2 (2 to 478 residues) using Met-Ala-Ser as substrate and manganese as co-facor preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed