Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50008708
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to human partial length FLT3 N841I mutant (V592 to Y969 residues) expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human partial length FLT3 K663Q mutant (V592 to Y969 residues) expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521506BDBM50521506(CHEMBL4551114)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  4.40nMAssay Description:Binding affinity to wild-type human partial length FLT3 (V592 to Y969 residues) expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  5.10nMAssay Description:Binding affinity to human partial length FLT3 D835H mutant (V592 to Y969 residues) expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521496BDBM50521496(CHEMBL4435457)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521476BDBM50521476(CHEMBL4517711)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521494BDBM50521494(CHEMBL4557634)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521498BDBM50521498(CHEMBL4572972)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  7nMAssay Description:Binding affinity to human partial length FLT3 D835V mutant (V592 to Y969 residues) expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50300690BDBM50300690(CHEMBL576982 | N-(5-tert-Butyl-isoxazol-3-yl)-N'-{...)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  7.80nMAssay Description:Binding affinity to human partial length FLT3 D835Y mutant (Q580 to Y969 residues) expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521505BDBM50521505(CHEMBL4441629)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521477BDBM50521477(CHEMBL4572804)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521489BDBM50521489(CHEMBL4440175)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  10nMAssay Description:Binding affinity to human partial length FLT3 R834Q mutant (V592 to Y969 residues) expressed in HEK293 cells measured after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521487BDBM50521487(CHEMBL4459941)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521480BDBM50521480(CHEMBL4441875)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521482BDBM50521482(CHEMBL4541344)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521478BDBM50521478(CHEMBL4475375)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521490BDBM50521490(CHEMBL4454804)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521497BDBM50521497(CHEMBL4461531)
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521479BDBM50521479(CHEMBL4435360)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521493BDBM50521493(CHEMBL4515336)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521507BDBM50521507(CHEMBL4575519)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  21nMAssay Description:Binding affinity to human partial length FLT3 ITD mutant expressed in Escherichia coli measured after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521504BDBM50521504(CHEMBL4472511)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521474BDBM50521474(CHEMBL4526888)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521502BDBM50521502(CHEMBL4539069)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521500BDBM50521500(CHEMBL4438587)
Affinity DataIC50: 26nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521472BDBM50521472(CHEMBL4569015)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521483BDBM50521483(CHEMBL4586009)
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521481BDBM50521481(CHEMBL4529106)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521491BDBM50521491(CHEMBL4532475)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521499BDBM50521499(CHEMBL4449006)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521484BDBM50521484(CHEMBL4553847)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521485BDBM50521485(CHEMBL4591906)
Affinity DataIC50: 38nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  41nMAssay Description:Binding affinity to human partial length FLT3 ITD/D835V double mutant expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521503BDBM50521503(CHEMBL4483045)
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataKd:  48nMAssay Description:Binding affinity to human partial length FLT3 ITD/F691L double mutant expressed in Escherichia coli after 1 hr by qPCR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521492BDBM50521492(CHEMBL4439044)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521473BDBM50521473(CHEMBL4558160)
Affinity DataIC50: 51nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521488BDBM50521488(CHEMBL4553033)
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521501BDBM50521501(CHEMBL4457542)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521486BDBM50521486(CHEMBL4442278)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521495BDBM50521495(CHEMBL4551816)
Affinity DataIC50: 86nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521475BDBM50521475(CHEMBL4533761)
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521508BDBM50521508(CHEMBL4468986)
Affinity DataIC50: 113nMAssay Description:Inhibition of recombinant human FLT3 (564 to end residues) using EAIYAAPFAKKK as substrate measured after 40 mins in presence of [gamma-33P]-ATP by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50521471BDBM50521471(CHEMBL4439404)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human c-Kit (544 to end residues) using poly(Glu, Tyr) 4:1 as substrate measured after 40 mins in presence of [gamma-33P]-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed