Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50008950
TargetLysine-specific demethylase 6B(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM60875(GSK-J1 | 3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H...)
Affinity DataIC50: 16nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM6B expressed in expressed in Sf9 cells pre-incubated for 4 hrs before substrate addition and measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50095446(CHEMBL3590426)
Affinity DataIC50: 79nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM5A expressed in Sf9 cells pre-incubated for 4 hrs before substrate addition and measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50523909(CHEMBL4456295)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM5A expressed in Sf9 cells pre-incubated for 4 hrs before substrate addition and measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50523910(CHEMBL4451372)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM5A expressed in Sf9 cells pre-incubated for 4 hrs before substrate addition and measured after 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 8.50E+4nMAssay Description:Inhibition of C-terminal FLAG-tagged human KDM4A expressed in Escherichia coli pre-incubated for 4 hrs before substrate addition and measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)