Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50008796
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522394(CHEMBL4472296)
Affinity DataIC50: 9nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522382(CHEMBL4450586)
Affinity DataIC50: 89nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522397(CHEMBL4440172)
Affinity DataIC50: 110nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522400(CHEMBL4562342)
Affinity DataIC50: 140nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522393(CHEMBL4572598)
Affinity DataIC50: 160nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522373(CHEMBL4472335)
Affinity DataIC50: 190nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522396(CHEMBL4447164)
Affinity DataIC50: 190nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522372(CHEMBL4473575)
Affinity DataIC50: 210nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522380(CHEMBL4562519)
Affinity DataIC50: 260nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522391(CHEMBL4462158)
Affinity DataIC50: 310nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522379(CHEMBL4583477)
Affinity DataIC50: 390nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522374(CHEMBL4471156)
Affinity DataIC50: 920nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522385(CHEMBL4455409)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522386(CHEMBL4543531)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522375(CHEMBL4473720)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522377(CHEMBL4571341)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522399(CHEMBL4456292)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522381(CHEMBL4466705)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522401(CHEMBL4541851)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522398(CHEMBL4551142)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522376(CHEMBL4448878)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522395(CHEMBL4553424)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522378(CHEMBL4464304)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522384(CHEMBL4561378)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522392(CHEMBL4530520)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522383(CHEMBL4556073)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522390(CHEMBL4561019)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522389(CHEMBL4438128)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522388(CHEMBL4447193)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522387(CHEMBL4538569)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50522371(CHEMBL4565311)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of smo-mediated hedgehog signaling pathway in mouse ASZ001 cells assessed as decrease in Gli1 mRNA expression after 48 hrs by qPCR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed