Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50007714
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 3nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512005(CHEMBL4440181)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Blk(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 10nMAssay Description:Inhibition of BLK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant LYN using biotinyl-beta amyloid beta amyloid beta AKVEKIGEGTYGVVYK as substrate measured after 120 mins in the presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD measured after 15 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant HER2 using biotinyl-beta amyloid beta amyloid beta AAEEEEYFELVAKKK measured after 10 mins in the presence of ATP by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant JAK3 using Ulight-CAGAGAIETDKEYYTVKD measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fgr(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant FGR using Ulight-TK peptide as substrate measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512009(CHEMBL4544821)
Affinity DataIC50: 31nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant LCK using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 10 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 33nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512002(CHEMBL4443198)
Affinity DataIC50: 37nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512003(CHEMBL4571839)
Affinity DataIC50: 42nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Tec(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 44nMAssay Description:Inhibition of TEC (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512000(CHEMBL4582791)
Affinity DataIC50: 45nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512007(CHEMBL4455094)
Affinity DataIC50: 46nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 83nMAssay Description:Inhibition of BMX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Yes(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant YES using biotinyl-beta amyloid beta amyloid beta AYQAEENTYDEYEN as substrate measured after 30 mins in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512004(CHEMBL4561220)
Affinity DataIC50: 89nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 123nMAssay Description:Inhibition of human recombinant SRC using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 10 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512006(CHEMBL4457802)
Affinity DataIC50: 123nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 232nMAssay Description:Inhibition of human recombinant FYN using biotinyl-beta amyloid beta amyloid beta AYQAEENTYDEYEN as substrate measured after 60 mins in the presence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 358nMAssay Description:Inhibition of human recombinant TXK using Ulight-Poly GAT[EAY(1:1:1) as substrate measured after 30 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 385nMAssay Description:Inhibition of HER4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512001(CHEMBL4535899)
Affinity DataIC50: 500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50512008(CHEMBL4588815)
Affinity DataIC50: 500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511999(CHEMBL4472161)
Affinity DataIC50: 500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511998(CHEMBL4514557)
Affinity DataIC50: 500nMAssay Description:Inhibition of BTK (unknown origin) in the presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant EGFR using Ulight-CAGAGAIETDKEYYTVKD measured after 15 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant JAK3 using Ulight-CAGAGAIETDKEYYTVKD measured after 60 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant ITK using Ulight-TK peptide as substrate measured after 30 mins in the presence of ATP by LANCE methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Sichuan University and Collaborative Innovation Center

Curated by ChEMBL
LigandPNGBDBM50511997(CHEMBL4525187)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant HER2 using biotinyl-beta amyloid beta amyloid beta AAEEEEYFELVAKKK measured after 10 mins in the presence of ATP by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed