Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50006975
TargetInterleukin-1 receptor antagonist protein(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 2nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505155(CHEMBL4455644)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505150(CHEMBL4537224)
Affinity DataIC50: 32nMAssay Description:Inhibition of human IRAP using L-leucine 7-amido-4-methyl coumarin substrate by microplate fluorescence reader based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 37nMAssay Description:Inhibition of ERAP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50245396(CHEMBL4101200)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505150(CHEMBL4537224)
Affinity DataIC50: 740nMAssay Description:Inhibition of ERAP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505150(CHEMBL4537224)
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505154(CHEMBL4581500)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50426080(CHEMBL2316257)
Affinity DataKi:  0.280nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target72 kDa type IV collagenase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505151(CHEMBL4520279)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human MMP2 by photoaffinity probe based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505151(CHEMBL4520279)
Affinity DataKi:  0.600nMAssay Description:Inhibition of human MMP8 by photoaffinity probe based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505152(CHEMBL4435285)
Affinity DataKi:  0.900nMAssay Description:Inhibition of human MMP12More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505151(CHEMBL4520279)
Affinity DataKi:  1nMAssay Description:Inhibition of human MMP12 by photoaffinity probe based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505151(CHEMBL4520279)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human MMP13 by photoaffinity probe based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505151(CHEMBL4520279)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human MMP9 by photoaffinity probe based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505156(CHEMBL4559677)
Affinity DataKi:  4.60nMAssay Description:Inhibition of human recombinant LTA4H by L-(4-benzoyl)phenylalanyl-beta-naphthylamide fluorigenic substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetLeukotriene A-4 hydrolase(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50505153(CHEMBL4543986)
Affinity DataKi:  5.30nMAssay Description:Inhibition of human recombinant LTA4H by L-(4-benzoyl)phenylalanyl-beta-naphthylamide fluorigenic substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  10nMAssay Description:Inhibition of Plasmodium falciparum LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  13nMAssay Description:Inhibition of Plasmodium falciparum LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  36nMAssay Description:Inhibition of porcine APNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  66nMAssay Description:Inhibition of porcine LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCytosol aminopeptidase(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190112(CHEMBL88808)
Affinity DataKi:  67nMAssay Description:Inhibition of porcine LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  276nMAssay Description:Inhibition of porcine APNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed