Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50007347
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508751(CHEMBL4559427)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508743(CHEMBL4460141)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508749(CHEMBL4546591)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508747(CHEMBL4591634)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508753(CHEMBL4580690)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508752(CHEMBL4474295)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508750(CHEMBL4521475)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508748(CHEMBL4440890)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508742(CHEMBL4558360)
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508752(CHEMBL4474295)
Affinity DataIC50: 78nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508749(CHEMBL4546591)
Affinity DataIC50: 141nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508742(CHEMBL4558360)
Affinity DataIC50: 148nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508753(CHEMBL4580690)
Affinity DataIC50: 170nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508744(CHEMBL4561864)
Affinity DataIC50: 182nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508743(CHEMBL4460141)
Affinity DataIC50: 209nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508746(CHEMBL4526092)
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508751(CHEMBL4559427)
Affinity DataIC50: 282nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508750(CHEMBL4521475)
Affinity DataIC50: 380nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508748(CHEMBL4440890)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508744(CHEMBL4561864)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508745(CHEMBL4462897)
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein O-GlcNAcase(Human)
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508746(CHEMBL4526092)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed