Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50010280
TargetFarnesyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(Bisphpshonate-715 | 3-(decyloxy)-1-(2-hydrogen pho...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(CHEMBL924 | [1-hydroxy-2-(1H-imidazol-1-yl)-1-phos...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGeranylgeranyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25259(Bisphpshonate-715 | 3-(decyloxy)-1-(2-hydrogen pho...)
Affinity DataIC50: 280nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25263({2-[3-(decyloxy)phenyl]-1-hydroxy-1-phosphonoethyl...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)(Escherichia coli (strain K12))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25271(3-[(3,7-dimethyloctyl)oxy]-1-(2-hydrogen phosphona...)
Affinity DataIC50: 6.60E+4nMAssay Description:Inhibition of Escherichia coli UPPS in presence of IPP and FPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM12578(CHEMBL924 | [1-hydroxy-2-(1H-imidazol-1-yl)-1-phos...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human GGPPSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFarnesyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50537059(CHEMBL4543393)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human FPPS using IPP and GPP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM25263({2-[3-(decyloxy)phenyl]-1-hydroxy-1-phosphonoethyl...)
Affinity DataIC50: 5.50E+5nMAssay Description:Inhibition of human FPPS using IPP and GPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed