Compile Data Set for Download or QSAR
Report error Found 63 Enz. Inhib. hit(s) with all data for entry = 50009763
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to mouse uPA by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKd:  11nMAssay Description:Binding affinity to mouse uPA expressed in HEK2936E cells by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKd:  42nMAssay Description:Binding affinity to mouse uPA expressed in HEK2936E cells by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKd:  354nMAssay Description:Binding affinity to mouse uPA expressed in HEK2936E cells by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKd:  398nMAssay Description:Binding affinity to mouse uPA by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKd:  15nMAssay Description:Binding affinity to mouse uPA by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataIC50: 10nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured immediatelyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataIC50: 11nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured at 8 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataIC50: 12nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured at 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataIC50: 71nMAssay Description:Inhibition of uPA in presence of 75% mouse serum measured at 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of the intrinsic peri-cellular uPA in mouse CT26 cells assessed as reduction in cell invasion measured every hour by transwell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of the intrinsic peri-cellular uPA in mouse CT26 cells assessed as reduction in cell invasion measured every hour by transwell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of the intrinsic peri-cellular uPA in mouse CT26 cells assessed as reduction in cell invasion measured every hour by transwell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi:  6.80nMAssay Description:Inhibition of mouse uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi:  15nMAssay Description:Inhibition of mouse uPA serine protease domain preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi:  20nMAssay Description:Inhibition of mouse uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi:  20nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi:  246nMAssay Description:Inhibition of mouse uPA serine protease domain preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi:  340nMAssay Description:Inhibition of human uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataKi:  370nMAssay Description:Inhibition of matriptase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataKi:  500nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi:  550nMAssay Description:Inhibition of mouse uPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi:  550nMAssay Description:Inhibition of mouse uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataKi:  650nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi:  903nMAssay Description:Inhibition of human uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataKi:  980nMAssay Description:Inhibition of factor 10a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataKi:  1.46E+3nMAssay Description:Inhibition of plasmin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of mouse uPA serine protease domain preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM23891(ethyl 4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-...)
Affinity DataKi:  2.51E+3nMAssay Description:Inhibition of tPA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibition of human uPA preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human activated protein C preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasma kallikrein(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasma kallikrein preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasma kallikrein(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasma kallikrein preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human factor 11a preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human matriptase preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human tissue-type plasminogen activator preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human plasma kallikrein preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse thrombin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse thrombin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human activated protein C preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human factor 11a preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of human thrombin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetPlasminogen(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse plasmin preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531924(CHEMBL4464577)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse tissue-type plasminogen activator preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531926(CHEMBL4550668)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse tissue-type plasminogen activator preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50531925(CHEMBL4522772)
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of mouse tissue-type plasminogen activator preincubated for 15 mins followed by chromogenic substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
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