Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50007815
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512893(CHEMBL4460096)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCaspase-9(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512892(CHEMBL4460352)
Affinity DataEC50:  240nMAssay Description:Inhibition of N-terminal CARD domain of caspase 9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM32580(CS-3)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM13169(H-N-Me-Ala-Tle-Pro-(S)-indan-1-yl Amide | (2S)-N-[...)
Affinity DataKd:  29nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512894(CHEMBL4518501)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to XIAP-BIR2/BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  50nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM32580(CS-3)
Affinity DataKd:  85nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCaspase-9(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataEC50:  290nMAssay Description:Inhibition of N-terminal CARD domain of caspase 9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512892(CHEMBL4460352)
Affinity DataKd:  5nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512893(CHEMBL4460096)
Affinity DataKd:  220nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  1nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKd:  17nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50441356(CHEMBL2431768)
Affinity DataKd:  53nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM26218((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataKd:  26nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512889(CHEMBL4518625)
Affinity DataKd:  200nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM32580(CS-3)
Affinity DataKd:  16nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 7(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  1nMAssay Description:Binding affinity to ML-IAP-BIR domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512894(CHEMBL4518501)
Affinity DataKd:  120nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512891(CHEMBL4459769)
Affinity DataKd:  16nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50071920(Birinapant | TL-32711)
Affinity DataKd:  36nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50441356(CHEMBL2431768)
Affinity DataKd:  13nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataEC50:  0.100nMAssay Description:Induction of cIAP1 (unknown origin) degradationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKd:  28nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKd:  112nMAssay Description:Binding affinity to XIAP-BIR2 domain (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKd:  43nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 7(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50388975(CHEMBL2063869)
Affinity DataKd:  14nMAssay Description:Binding affinity to ML-IAP-BIR domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50441356(CHEMBL2431768)
Affinity DataKd:  10nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512889(CHEMBL4518625)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM13167((2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)p...)
Affinity DataKd:  12nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCaspase-9(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512891(CHEMBL4459769)
Affinity DataEC50:  310nMAssay Description:Inhibition of N-terminal CARD domain of caspase 9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512890(CHEMBL4575701)
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to XIAP-BIR2/BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512890(CHEMBL4575701)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of of XIAP-BIR2/BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50: 15nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50: 15nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512888(CHEMBL4452928)
Affinity DataIC50: 17nMAssay Description:Binding affinity to XIAP-BIR3 domain (241 to 356 residues) (unknown origin) by fluorescence polarization-based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50: 21nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50: 21nMAssay Description:Binding affinity to XIAP-BIR2 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512888(CHEMBL4452928)
Affinity DataIC50: 200nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 3(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512888(CHEMBL4452928)
Affinity DataIC50: 353nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50512895(CHEMBL4582246)
Affinity DataIC50: 376nMAssay Description:Binding affinity to XIAP-BIR2/BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM26218((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataIC50: 438nMAssay Description:Binding affinity to XIAP-BIR2/BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM26218((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataIC50: 438nMAssay Description:Inhibition of of XIAP-BIR2/BIR3 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM26218((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(methyla...)
Affinity DataIC50: 5.60E+3nMAssay Description:Binding affinity to XIAP-BIR2 domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed