Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50008676
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM524922(US11168095, Example 163 | BDBM50521256)
Affinity DataIC50: 100nMAssay Description:Inhibition of full-length human GST-tagged ASK1 expressed in baculovirus expression system using biotinylated STK Substrate 3 preincubated for 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50505958(CHEMBL4447729 | US11168095, Example 171)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant V5-tagged ASK1 (unknown origin) expressed in HEK293 cells assessed as reduction in ASK1 autophosphorylation at T838 residue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM524922(US11168095, Example 163 | BDBM50521256)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant V5-tagged ASK1 (unknown origin) expressed in HEK293 cells assessed as reduction in ASK1 autophosphorylation at T838 residue...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed