Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50009184
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196528(CHEMBL3923120 | US10167270, Example 00161 | US1050...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196514(CHEMBL3950881 | US10167270, Example 00159)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196622(CHEMBL3923147 | US10167270, Example 00160 | US1050...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196531(CHEMBL3964444 | US10167270, Compound 7a)
Affinity DataIC50: 27nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196530(CHEMBL3974789 | US10167270, Compound 7b)
Affinity DataIC50: 42nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50033286(Phenethyl-(2-pyridin-3-yl-quinazolin-4-yl)-amine; ...)
Affinity DataIC50: 97nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196518(CHEMBL3920301 | US10167270, Compound 4)
Affinity DataIC50: 177nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313305(US10167270, Example 84)
Affinity DataIC50: 430nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196516(CHEMBL3968279 | US10167270, Compound 7c)
Affinity DataIC50: 720nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196626(CHEMBL3972062 | US10167270, Compound 8e)
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50196630(CHEMBL3942452 | US10167270, Compound 8d)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313417(US10167270, Example 97)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313224(US10167270, Example 2)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313411(US10167270, Example 91)
Affinity DataIC50: 2.54E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313412(US10167270, Example 92)
Affinity DataIC50: 4.24E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50525974(CHEMBL4444925)
Affinity DataIC50: 5.87E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313443(US10167270, Example 140)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50525975(CHEMBL4530904)
Affinity DataIC50: 8.38E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM313430(US10167270, Example 121)
Affinity DataIC50: 9.94E+3nMAssay Description:Inhibition of wild type recombinant human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed