Compile Data Set for Download or QSAR
Report error Found 47 Enz. Inhib. hit(s) with all data for entry = 50004987
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537560(CHEMBL427101)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537561(CHEMBL388502)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537562(CHEMBL223720)
Affinity DataKd:  720nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50: 2nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537589(CHEMBL4287268)
Affinity DataIC50: 3nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537581(CHEMBL4638107)
Affinity DataIC50: 4nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537583(CHEMBL4638630)
Affinity DataIC50: 4.30nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537585(CHEMBL4646449)
Affinity DataIC50: 5nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537587(CHEMBL4633142)
Affinity DataIC50: 6nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537579(CHEMBL4635161)
Affinity DataIC50: 6nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537578(CHEMBL245328)
Affinity DataIC50: 7.20nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50379197(CHEMBL2011266)
Affinity DataIC50: 8nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537574(CHEMBL4643906)
Affinity DataIC50: 10nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537575(CHEMBL4638877)
Affinity DataIC50: 10nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537588(CHEMBL4643189)
Affinity DataIC50: 17nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50142061(2-{4-[4''-Chloro-4-(4-hydroxy-piperidine-1-carbony...)
Affinity DataIC50: 19nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50081635(CHEMBL3422107)
Affinity DataIC50: 19nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537580(CHEMBL480816)
Affinity DataIC50: 27nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537566(CHEMBL4640558)
Affinity DataIC50: 33nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537586(CHEMBL4641917)
Affinity DataIC50: 39nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537571(CHEMBL390883)
Affinity DataIC50: 42nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537565(CHEMBL4649647)
Affinity DataIC50: 51nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537584(CHEMBL4636786)
Affinity DataIC50: 53nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50187149(6-cyclohexyl-4-(2-(dimethylamino)-2-oxoethyl)-5-ph...)
Affinity DataIC50: 58nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537582(CHEMBL1783101)
Affinity DataIC50: 70nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50137504(1-Cyclohexyl-2-furan-2-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50: 160nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537572(CHEMBL1087567)
Affinity DataIC50: 300nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537576(CHEMBL4633554)
Affinity DataIC50: 340nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50370763(CHEMBL1203926)
Affinity DataIC50: 340nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50160199(6,7-Bis-(4-fluoro-phenyl)-pteridin-4-ol | CHEMBL18...)
Affinity DataIC50: 500nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537573(CHEMBL4642429)
Affinity DataIC50: 550nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537577(CHEMBL4639473)
Affinity DataIC50: 600nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537567(CHEMBL4632418)
Affinity DataIC50: 800nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50137488(1-Cyclohexyl-2-furan-3-yl-1H-benzoimidazole-5-carb...)
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537559(CHEMBL4640738)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50181949(2-(4-(benzyloxy)phenyl)-1-cyclopentyl-1H-benzo[d]i...)
Affinity DataIC50: 3.20E+3nMAssay Description:Binding affinity to HCV NS5A polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537591(CHEMBL3617579)
Affinity DataIC50: 8.80E+3nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537568(CHEMBL4641913)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537590(CHEMBL4641216)
Affinity DataIC50: 1.57E+4nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537570(CHEMBL474496)
Affinity DataIC50: 4.50E+4nMAssay Description:Binding affinity to HCV NS5B polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537558(Narlaprevir | SCH 900518 | SCH-900518)
Affinity DataKi:  6nMAssay Description:Inhibition of HCV NS3/4a protease using Ac-DE-Dap(QXL520)-EE-Abu-shi-[COO]AS-C(5-FAMsp)-NH2 as substrate after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537563(CHEMBL4634405)
Affinity DataKi:  20nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50103860(2-{[2-(6-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataKi:  27nMAssay Description:Inhibition of HCV NS3/4a protease in presence Zn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537564(CHEMBL4644516)
Affinity DataKi:  40nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50537569(CHEMBL4646328)
Affinity DataKi:  600nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepacivirus C)
Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50103860(2-{[2-(6-Carbamoyl-1H-benzoimidazol-2-ylmethyl)-3-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of HCV NS3/4a proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed