Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50008287
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM5446(Erlotinib | OSI-774 | N-(3-ethynylphenyl)-6,7-bis(...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517548(CHEMBL4460381)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517546(CHEMBL4473768)
Affinity DataIC50: 10nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517542(CHEMBL4569885)
Affinity DataIC50: 30nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517545(CHEMBL4546122)
Affinity DataIC50: 52nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50137185((1H-Indol-5-yl)-(6-phenyl-thieno[3,2-d]pyrimidin-4...)
Affinity DataIC50: 80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50137204((2-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)
Affinity DataIC50: 100nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50137204((2-Methyl-1H-indol-5-yl)-(6-phenyl-thieno[3,2-d]py...)
Affinity DataIC50: 140nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataIC50: 140nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517544(CHEMBL4552482)
Affinity DataIC50: 273nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517543(CHEMBL4572443)
Affinity DataIC50: 326nMAssay Description:Inhibition of wild type EGFR (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517542(CHEMBL4569885)
Affinity DataIC50: 710nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517546(CHEMBL4473768)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517548(CHEMBL4460381)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517545(CHEMBL4546122)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517542(CHEMBL4569885)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type VEGFR2 (unknown origin) by bioluminescent ADP-glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50005480(combretastin A4 | CHEMBL67 | 2-Methoxy-5-[2-(3,4,5...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517546(CHEMBL4473768)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517543(CHEMBL4572443)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517545(CHEMBL4546122)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517544(CHEMBL4552482)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517547(CHEMBL4541014)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50517548(CHEMBL4460381)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of bovine brain tubulin polymerization after 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed