Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50007316
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508568(CHEMBL4474886)
Affinity DataKd:  1.38E+4nMAssay Description:Binding affinity to recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21 (DE3) by surface...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataKd:  1.58E+4nMAssay Description:Binding affinity to recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21 (DE3) by surface...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50164787(CHEMBL3798088)
Affinity DataIC50: 0.900nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataIC50: 2.40nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200712(US9233086, 10A)
Affinity DataIC50: 2.90nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200722(US9233086, 10K)
Affinity DataIC50: 4.5nMAssay Description:Displacement of fluorescence-labelled Ac-ARA peptide from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508568(CHEMBL4474886)
Affinity DataIC50: 9.63E+3nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508575(CHEMBL4464601)
Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508574(CHEMBL4435564)
Affinity DataIC50: 1.36E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508567(CHEMBL4578737)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508580(CHEMBL4557413)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508578(CHEMBL4579304)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508576(CHEMBL4449119)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508572(CHEMBL4514062)
Affinity DataIC50: 2.30E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508571(CHEMBL4469769)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508566(CHEMBL4435755)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508570(CHEMBL4534707)
Affinity DataIC50: 2.50E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508573(CHEMBL4455781)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508579(CHEMBL4453261)
Affinity DataIC50: 3.80E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508577(CHEMBL4452985)
Affinity DataIC50: 4.80E+4nMAssay Description:Displacement of Ac-ARTEVHLRKS-(Ahx)-(Ahx)-K(5-FAM)-NH2 from recombinant full-length human N-terminal His6-tagged WDR5 (1 to 334 residues) expressed i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase SETD1B(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SETD1B (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alpha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase 2D(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLL2 (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alphali...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PRMT1 (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alphal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50508569(CHEMBL4557353)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of G9a (unknown origin) using SAM as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by Alphalis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200712(US9233086, 10A)
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetWD repeat-containing protein 5(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM200722(US9233086, 10K)
Affinity DataKi: <1nMAssay Description:Displacement of 5-FAM labelled tracer from WDR5 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed