Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 50009564
TargetSterol 14-alpha demethylase(Trypanosoma cruzi (strain CL Brener))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataKd:  5.50E+3nMAssay Description:Binding affinity to Trypanosoma cruzi CYP51 by UV-vis spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSterol 14-alpha demethylase(Trypanosoma cruzi (strain CL Brener))
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataKd:  5.50E+3nMAssay Description:Binding affinity to Trypanosoma cruzi CYP51 by UV-vis spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataIC50: 400nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529952(CHEMBL315874)
Affinity DataIC50: 800nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529952(CHEMBL315874)
Affinity DataIC50: 800nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529949(CHEMBL4438726)
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529950(CHEMBL4551139)
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529949(CHEMBL4438726)
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529950(CHEMBL4551139)
Affinity DataIC50: 900nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529948(CHEMBL4569370)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529948(CHEMBL4569370)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529950(CHEMBL4551139)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529950(CHEMBL4551139)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529952(CHEMBL315874)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529952(CHEMBL315874)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human CYP3A4 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529950(CHEMBL4551139)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529948(CHEMBL4569370)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529948(CHEMBL4569370)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529950(CHEMBL4551139)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50236897(furafylline | 3-(furan-2-ylmethyl)-1,8-dimethyl-1H...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529948(CHEMBL4569370)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529948(CHEMBL4569370)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529951(CHEMBL4468270)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529949(CHEMBL4438726)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529949(CHEMBL4438726)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human CYP2D6 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529952(CHEMBL315874)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529952(CHEMBL315874)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529949(CHEMBL4438726)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
"Sapienza" Universit£

Curated by ChEMBL
LigandPNGBDBM50529949(CHEMBL4438726)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP1A2 in presence of NADPH by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed