Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50009729
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 347nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 350nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50: 759nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)
Affinity DataIC50: 760nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531689(CHEMBL4483431)
Affinity DataIC50: 1.18E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531680(CHEMBL4562432)
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531689(CHEMBL4483431)
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531680(CHEMBL4562432)
Affinity DataIC50: 1.23E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531678(CHEMBL4526190)
Affinity DataIC50: 1.30E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531678(CHEMBL4526190)
Affinity DataIC50: 1.32E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531681(CHEMBL4453525)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531681(CHEMBL4453525)
Affinity DataIC50: 1.45E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531691(CHEMBL4463654)
Affinity DataIC50: 1.60E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531691(CHEMBL4463654)
Affinity DataIC50: 1.62E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531682(CHEMBL4547249)
Affinity DataIC50: 2.80E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531682(CHEMBL4547249)
Affinity DataIC50: 2.82E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531683(CHEMBL4445412)
Affinity DataIC50: 3.09E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531683(CHEMBL4445412)
Affinity DataIC50: 3.10E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531686(CHEMBL4467263)
Affinity DataIC50: 5.89E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531686(CHEMBL4467263)
Affinity DataIC50: 5.90E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531690(CHEMBL4442991)
Affinity DataIC50: 7.90E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531690(CHEMBL4442991)
Affinity DataIC50: 7.94E+3nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 8(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu8 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531688(CHEMBL4476165)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531684(CHEMBL4467232)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531685(CHEMBL4563163)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu5 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 6(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531687(CHEMBL4445682)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of mGlu6 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531677(CHEMBL4557757)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531679(CHEMBL4558834)
Affinity DataIC50: 3.16E+4nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531688(CHEMBL4476165)
Affinity DataIC50: 1.00E+7nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Rat)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50531679(CHEMBL4558834)
Affinity DataIC50: 3.00E+7nMAssay Description:Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed