Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50007272
LigandChemical structure of BindingDB Monomer ID 50507856BDBM50507856(CHEMBL4483603)
Affinity DataIC50: 2nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 15nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507845BDBM50507845(CHEMBL4455868)
Affinity DataIC50: 18nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507851BDBM50507851(CHEMBL4474590)
Affinity DataIC50: 24nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507854BDBM50507854(CHEMBL4562194)
Affinity DataIC50: 31nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507855BDBM50507855(CHEMBL4564889)
Affinity DataIC50: 43nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507848BDBM50507848(CHEMBL4457824)
Affinity DataIC50: 43nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507840BDBM50507840(CHEMBL4452291)
Affinity DataIC50: 45nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507861BDBM50507861(CHEMBL4571436)
Affinity DataIC50: 59nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507837BDBM50507837(CHEMBL4546247)
Affinity DataIC50: 65nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507862BDBM50507862(CHEMBL4521566)
Affinity DataIC50: 95nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507850BDBM50507850(CHEMBL4468605)
Affinity DataIC50: 106nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507863BDBM50507863(CHEMBL4590816)
Affinity DataIC50: 130nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507849BDBM50507849(CHEMBL4583673)
Affinity DataIC50: 227nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507846BDBM50507846(CHEMBL4447338)
Affinity DataIC50: 534nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507844BDBM50507844(CHEMBL4453894)
Affinity DataIC50: 579nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507836BDBM50507836(CHEMBL4443309)
Affinity DataIC50: 593nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507835BDBM50507835(CHEMBL4466809)
Affinity DataIC50: 607nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507859BDBM50507859(CHEMBL4534370)
Affinity DataIC50: 708nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507847BDBM50507847(CHEMBL4458495)
Affinity DataIC50: 728nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507853BDBM50507853(CHEMBL4557777)
Affinity DataIC50: 742nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507852BDBM50507852(CHEMBL4456468)
Affinity DataIC50: 797nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507858BDBM50507858(CHEMBL4531177)
Affinity DataIC50: 998nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507841BDBM50507841(CHEMBL4591193)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507857BDBM50507857(CHEMBL4590524)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507843BDBM50507843(CHEMBL4442118)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507838BDBM50507838(CHEMBL4569172)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507842BDBM50507842(CHEMBL4455092)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507860BDBM50507860(CHEMBL4587225)
Affinity DataIC50: 2.57E+3nMAssay Description:Inhibition of human Nav1.8 expressed in HEK cells by patch-clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507840BDBM50507840(CHEMBL4452291)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv1.5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv1.2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetVoltage-gated T-type calcium channel(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of T-type calcium channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of KvLQT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Kv1.1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of L-type calcium channel (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.6More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507839BDBM50507839(PF-6305591 | Pf-06305591)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GABA receptor alpha1gamma2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507835BDBM50507835(CHEMBL4466809)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50507840BDBM50507840(CHEMBL4452291)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed