Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50008359
Target72 kDa type IV collagenase(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of MMP2 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of MMP9 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50518450(CHEMBL4591371)
Affinity DataIC50: 190nMAssay Description:Inhibition of MMP2 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50518450(CHEMBL4591371)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of MMP9 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50518449(CHEMBL4435950)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of MMP2 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50518449(CHEMBL4435950)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of MMP9 (unknown origin) preincubated for 1 hr followed by (QF)-24 substrate addition measured at 1 min time interval for 1 hr by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetAminopeptidase N(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50518449(CHEMBL4435950)
Affinity DataKi:  300nMAssay Description:Inhibition of human APN expressed in HEK293 cells preincubated for 20 mins followed by L-leucine-7-amido-4-methylcoumarin addition by fluorescence as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed