Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50007195
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 260nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid as substrate preincubated for 20 mins followed by substrate addition measured at 1 sec int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 540nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507265(CHEMBL4536074)
Affinity DataIC50: 600nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507267(CHEMBL4444061)
Affinity DataIC50: 600nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM198173(2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...)
Affinity DataIC50: 600nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50: 600nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM198172(2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...)
Affinity DataIC50: 600nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50029593(CHEMBL7162 | NS398 | NS-398 | N-(2-Cyclohexyloxy-4...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Sheep)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507268(CHEMBL4456497)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507266(CHEMBL4555690)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507264(CHEMBL4466839)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507263(CHEMBL4474936)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507262(CHEMBL4443940)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Universidad Tecnol£Gica De Pereira

Curated by ChEMBL
LigandPNGBDBM50507261(CHEMBL4437353)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid as substrate preincubated for 20 mins followed by substrate addition measured at 1 sec int...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed