Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50009705
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.67E+3nMAssay Description:Inhibition of recombinant full length human GST-tagged SHP2 E76K mutant using pNPP as substrate pre-incubated for 15 mins before pNPP substrate addit...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of wild type recombinant human SHP2 using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate preincubated for 30 ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of recombinant full length human GST-tagged SHP2 PTP domain using pNPP as substrate pre-incubated for 15 mins before pNPP substrate additi...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataKd: 6.90E+4nMAssay Description:Binding affinity to full length wild type His-tagged SHP2 (unknown origin) by MST assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 7.27E+4nMAssay Description:Inhibition of wild type recombinant human SHP1 using H-Glu-Phe-pTyr-Ala-Glu-Val-Gly-Arg-Ser-Pro-Pro-Asp-Pro-Ala-Lys as substrate preincubated for 30 ...More data for this Ligand-Target Pair
