Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50006820
TargetCathepsin B(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503648(CHEMBL4474444)
Affinity DataKi:  340nMAssay Description:Inhibition of cathepsin B (unknown origin) using Z-Arg-Arg-AMC as substrate after 5 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503648(CHEMBL4474444)
Affinity DataKi:  720nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-Phe-Arg-AMC as substrate after 5 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503647(CHEMBL327624)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-Phe-Arg-AMC as substrate after 5 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503647(CHEMBL327624)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of cathepsin B (unknown origin) using Z-Arg-Arg-AMC as substrate after 5 mins by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503646(CHEMBL4564457)
Affinity DataKi:  5.90E+4nMAssay Description:Competitive inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured at 1 min interval for 20 mins followed by every 15 mins for 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503650(CHEMBL4516952)
Affinity DataKi:  1.46E+5nMAssay Description:Inhibition of human liver cathepsin L using Z-FR-AMC as substrate measured at 1 min interval for 20 mins followed by every 15 mins for 2 hrs by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGTPase KRas(Human)
University of Houston

Curated by ChEMBL
LigandPNGBDBM50503649(CHEMBL4476113)
Affinity DataKi:  2.00E+5nMAssay Description:Inhibition of KRAS G12C mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed