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Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50008618
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant thrombin expressed in HEK293 cells using S-2238 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249298(N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human recombinant thrombin expressed in HEK293 cells using S-2238 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 10nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 12nMAssay Description:Inhibition of human factor 7a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50249298(N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbami...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant thrombin expressed in HEK293 cells using S-2238 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520870(CHEMBL4439939)
Affinity DataIC50: 18nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 18nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520881(CHEMBL4530584)
Affinity DataIC50: 20nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520875(CHEMBL4574442)
Affinity DataIC50: 24nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520865(CHEMBL4469752)
Affinity DataIC50: 26nMAssay Description:Inhibition of human factor 9a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520878(CHEMBL4586397)
Affinity DataIC50: 30nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant thrombin expressed in HEK293 cells using S-2238 as substrate preincubated for 30 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520867(CHEMBL4441346)
Affinity DataIC50: 36nMAssay Description:Inhibition of human factor 9a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 42nMAssay Description:Inhibition of human factor 9a preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520879(CHEMBL4514976)
Affinity DataIC50: 45nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetTrypsin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520866(CHEMBL4469308)
Affinity DataIC50: 54nMAssay Description:Inhibition of human trypsin preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520876(CHEMBL4450264)
Affinity DataIC50: 77nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520872(CHEMBL4530694)
Affinity DataIC50: 179nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520873(CHEMBL4459345)
Affinity DataIC50: 234nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520882(CHEMBL4543553)
Affinity DataIC50: 246nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520869(CHEMBL4438123)
Affinity DataIC50: 272nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520883(CHEMBL4445604)
Affinity DataIC50: 315nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520868(CHEMBL4572670)
Affinity DataIC50: 513nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520863(CHEMBL4470300)
Affinity DataIC50: 653nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520874(CHEMBL4439436)
Affinity DataIC50: 981nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520862(CHEMBL4448395)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520864(CHEMBL4525969)
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520880(CHEMBL4472454)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520871(CHEMBL4472318)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50520877(CHEMBL4439648)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of human factor Xa using S-2222 as substrate preincubated for 30 mins followed by substrate addition and measured for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed