Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50003205
TargetProthrombin(Human)
Institute of Medicinal and Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197(stigmast-5-en-3beta-ol | sitosterol | (-)-beta-Sit...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of thrombin in human washed platelets assessed as reduction in thrombin-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Institute of Medicinal and Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197(stigmast-5-en-3beta-ol | sitosterol | (-)-beta-Sit...)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of thrombin in human platelet rich plasma assessed as reduction in thrombin-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Institute of Medicinal and Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197(stigmast-5-en-3beta-ol | sitosterol | (-)-beta-Sit...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of thrombin in human platelet rich plasma assessed as reduction in arachidonic acid-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Institute of Medicinal and Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197(stigmast-5-en-3beta-ol | sitosterol | (-)-beta-Sit...)
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of thrombin in human platelet rich plasma assessed as reduction in ADP-induced platelet aggregation after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Institute of Medicinal and Aromatic Plants

Curated by ChEMBL
LigandPNGBDBM50218197(stigmast-5-en-3beta-ol | sitosterol | (-)-beta-Sit...)
Affinity DataKi:  267nMAssay Description:Uncompetitive inhibition of human thrombin using T1637 as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed