Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50003153
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50448936(CHEMBL3125527 | US9296736, 342 | US9593129, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of p53-MDM2 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50448969(CHEMBL3125517 | US9296736, 256 | US9593129, Exampl...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p53-MDM2 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50467678(Ds-3032 | Milademetan)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50087289(4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-o...)
Affinity DataIC50: 20nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM129823(US8815926, 102)
Affinity DataKi:  0.210nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
International Institute For Translational Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50433561(CHEMBL2381408)
Affinity DataKi:  0.880nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed