Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50003295
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50394674(CHEMBL2165254)
Affinity DataIC50: 283nMAssay Description:Inhibition of rat liver ACLY by MDH enzyme coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469147(CHEMBL4281691)
Affinity DataIC50: 6.18E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50394675(PURPURONE)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of ACLY (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469153(CHEMBL4292319)
Affinity DataIC50: 9.63E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50066694((S)-2-[(R)-7-(3-Chloro-9H-fluoren-9-yl)-2-hydroxy-...)
Affinity DataKi:  220nMAssay Description:Inhibition of human ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50394677(CHEMBL2165262)
Affinity DataKi:  700nMAssay Description:Competitive inhibition of human liver ACLY using varying levels of citrate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of rat ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50053000(2-[8-(2,4-Dichloro-phenyl)-2-oxo-octyl]-2-hydroxy-...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50053001(2-[6-(2,4-Dichloro-phenyl)-hexylsulfanylmethyl]-su...)
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50052989(2-[8-(2,4-Dichloro-phenyl)-octyl]-2-hydroxy-succin...)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50394678(CHEMBL2165261)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of human liver ACLY using varying levels of citrate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50053020(2-[6-(2,4-Dichloro-phenyl)-hexylsulfanylmethyl]-2-...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469149(CHEMBL4283629)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469152(CHEMBL4290816)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469151(CHEMBL4280177)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469150(CHEMBL4287406)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM227589(Radicicol)
Affinity DataKi:  7.00E+3nMAssay Description:Non-competitive inhibition of rat liver ACLY using citrate substrate and varying levels of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50036210((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM227589(Radicicol)
Affinity DataKi:  1.30E+4nMAssay Description:Non-competitive inhibition of rat liver ACLY using varying levels of citrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50018569(CHEMBL63829 | 3,3,14,14-Tetramethyl-hexadecanedioi...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50036215((2S,3R)-2-Carboxymethyl-oxirane-2,3-dicarboxylic a...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50394667(CHEMBL2165253)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50469148(CHEMBL357626)
Affinity DataKi:  2.50E+5nMAssay Description:Reversible inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Rat)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM17657(L-Glutamic acid | L-Glu | (2S)-2-aminopentanedioic...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of rat liver ACLYMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50036210((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...)
Affinity DataKi:  3.00E+5nMAssay Description:Competitive inhibition of human liver ACLY using varying levels of citrate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)