Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50002459
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458775(CHEMBL4218415)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458774(CHEMBL4202714)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458763(CHEMBL4202848)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458764(CHEMBL4209125)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458765(CHEMBL4205697)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458773(CHEMBL4204567)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458758(CHEMBL4207907)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458776(CHEMBL4202960)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458759(CHEMBL4202420)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human full length TLL1 using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2) as substrate preincubated for 10 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458761(CHEMBL4206785)
Affinity DataIC50: 126nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 2(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal 6His-tagged TLL2 (26 to 1015 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458767(CHEMBL4218334)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458769(CHEMBL4218229)
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458772(CHEMBL4211663)
Affinity DataIC50: 200nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458767(CHEMBL4218334)
Affinity DataIC50: 400nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458770(CHEMBL4211285)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458770(CHEMBL4211285)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458769(CHEMBL4218229)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458760(CHEMBL4205331)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458768(CHEMBL4215581)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458760(CHEMBL4205331)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458768(CHEMBL4215581)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458772(CHEMBL4211663)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal 6His/flag-tagged BMP1 (121 to 721 residues) expressed in CHO cells using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458761(CHEMBL4206785)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458762(CHEMBL4207308)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)
Affinity DataKi:  0.00680nMAssay Description:Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)
Affinity DataKi:  0.0310nMAssay Description:Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 2(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458766(CHEMBL4212386)
Affinity DataKi:  0.0390nMAssay Description:Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to BMP1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate preincubated for 3 hrs followed by subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 1(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)
Affinity DataKi:  0.240nMAssay Description:Binding affinity to TLL1 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTolloid-like protein 2(Human)
Glaxosmithkline Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50458771(CHEMBL4214046)
Affinity DataKi:  0.260nMAssay Description:Binding affinity to TLL2 (unknown origin) using ((5-FAM)-ELIDQYDVQRDDSSDGSLED-K(5,6 TAMRA)-CONH2 as substrate incubated for 3.5 hrs followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed