Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50003012
TargetOxysterols receptor LXR-beta(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465710(CHEMBL4289727)
Affinity DataEC50:  720nMAssay Description:Agonist activity at GAL4-tagged human LXRbeta LBD expressed in HEK293T cells after 12 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50034786(CHEMBL3360964)
Affinity DataEC50:  108nMAssay Description:Agonist activity at human full length LXRbeta expressed in African green monkey CV-1 cells co-expressing human pCMX/RXRalpha after 20 hrs by lucifera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50:  530nMAssay Description:Agonist activity at human LXRbeta-LBD (196 to 461 amino acids) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM20186((4R)-4-[(1S,2R,5S,10S,11S,14R,15R)-5-hydroxy-2,15-...)
Affinity DataEC50:  422nMAssay Description:Agonist activity at human LXRalpha expressed in HEK293 cells after 24 hrs by One-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465711(CHEMBL1316881)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human LXRalpha-LBD (182 to 447 amino acids) expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465713(CHEMBL4277633 | US20230340011, Example 94.)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human LXRalpha expressed in HEK293 cells after 24 hrs by One-Glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465712(CHEMBL4284414)
Affinity DataIC50: 43nMAssay Description:Inverse agonist activity at LXRbeta (unknown origin) expressed in HEK293 cells 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50465712(CHEMBL4284414)
Affinity DataIC50: 214nMAssay Description:Inverse agonist activity at LXRalpha (unknown origin) expressed in HEK293 cells 24 hrs by Dual-Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human LXRalpha expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed