Compile Data Set for Download or QSAR
Report error Found 293 Enz. Inhib. hit(s) with all data for entry = 50001755
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366426(CHEMBL4161819)
Affinity DataIC50: 17nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366379(CHEMBL4165249)
Affinity DataIC50: 42nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366334(CHEMBL4173133)
Affinity DataIC50: 51nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366391(CHEMBL4173088)
Affinity DataIC50: 55nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366395(CHEMBL4175869)
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366411(CHEMBL4160749)
Affinity DataIC50: 62nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366399(CHEMBL4168669)
Affinity DataIC50: 73nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366411(CHEMBL4160749)
Affinity DataIC50: 76nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366379(CHEMBL4165249)
Affinity DataIC50: 87nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366426(CHEMBL4161819)
Affinity DataIC50: 93nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366407(CHEMBL4169324)
Affinity DataIC50: 110nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366435(CHEMBL4161400)
Affinity DataIC50: 120nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366398(CHEMBL4164113)
Affinity DataIC50: 130nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366401(CHEMBL4169721)
Affinity DataIC50: 140nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM12348(US8609708, 3 | 3-(pyridin-3-yl)prop-2-yn-1-amine |...)
Affinity DataIC50: 160nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366399(CHEMBL4168669)
Affinity DataIC50: 160nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366394(CHEMBL4159065)
Affinity DataIC50: 180nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366379(CHEMBL4165249)
Affinity DataIC50: 190nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366399(CHEMBL4168669)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366393(CHEMBL4176100)
Affinity DataIC50: 220nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366407(CHEMBL4169324)
Affinity DataIC50: 230nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366426(CHEMBL4161819)
Affinity DataIC50: 230nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366334(CHEMBL4173133)
Affinity DataIC50: 260nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366435(CHEMBL4161400)
Affinity DataIC50: 260nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366401(CHEMBL4169721)
Affinity DataIC50: 260nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366411(CHEMBL4160749)
Affinity DataIC50: 270nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366394(CHEMBL4159065)
Affinity DataIC50: 290nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366435(CHEMBL4161400)
Affinity DataIC50: 290nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366408(CHEMBL4176506)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366414(CHEMBL4172017)
Affinity DataIC50: 330nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366401(CHEMBL4169721)
Affinity DataIC50: 370nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366401(CHEMBL4169721)
Affinity DataIC50: 370nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366335(CHEMBL4165895)
Affinity DataIC50: 380nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366392(CHEMBL4172417)
Affinity DataIC50: 390nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366394(CHEMBL4159065)
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366395(CHEMBL4175869)
Affinity DataIC50: 410nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366400(CHEMBL4171984)
Affinity DataIC50: 440nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366403(CHEMBL4164142)
Affinity DataIC50: 460nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366402(CHEMBL4172462)
Affinity DataIC50: 550nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366410(CHEMBL4163694)
Affinity DataIC50: 560nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366397(CHEMBL4170930)
Affinity DataIC50: 590nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366406(CHEMBL4174365)
Affinity DataIC50: 670nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366395(CHEMBL4175869)
Affinity DataIC50: 760nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins followed by addition of NADPH-regenerating...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366411(CHEMBL4160749)
Affinity DataIC50: 810nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2A6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366405(CHEMBL4175429)
Affinity DataIC50: 830nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366426(CHEMBL4161819)
Affinity DataIC50: 840nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366393(CHEMBL4176100)
Affinity DataIC50: 850nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366394(CHEMBL4159065)
Affinity DataIC50: 850nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 5 mins followed by addition of NADPH-regenerating...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366395(CHEMBL4175869)
Affinity DataIC50: 910nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366402(CHEMBL4172462)
Affinity DataIC50: 920nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using omeprazole as substrate preincubated for 5 mins followed by addition of NADPH-regenerating syst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
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