Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50002758
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462578(CHEMBL4239697)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50044548(CHEMBL3314092)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462582(CHEMBL4250783)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462576(CHEMBL4249808)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50044548(CHEMBL3314092)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462581(CHEMBL4246013)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462580(CHEMBL4239268)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  16nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462581(CHEMBL4246013)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462577(CHEMBL4243833)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50044549(CHEMBL3314093)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462580(CHEMBL4239268)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462578(CHEMBL4239697)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462577(CHEMBL4243833)
Affinity DataKd:  0nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462576(CHEMBL4249808)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50044549(CHEMBL3314093)
Affinity DataKd:  0nMAssay Description:Inhibition of mouse AChE active site after 12 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM84460(HIV-1 PR Inhibitor, compound 6)
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 protease after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetChitinase B(Serratia marcescens)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462584(CHEMBL4245260)
Affinity DataIC50: 22nMAssay Description:Inhibition of Serratia marcescens 6x-His-tagged ChiB after 20 hrs by LCMS-SIR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInsulin-degrading enzyme(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462574(CHEMBL4241044)
Affinity DataIC50: 56nMAssay Description:Inhibition of human IDE using insulin as substrate preincubated for 10 mis followed by substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462579(CHEMBL4250387)
Affinity DataIC50: 59nMAssay Description:Inhibition of CA2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHTH-type transcriptional regulator EthR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462583(CHEMBL1234901)
Affinity DataIC50: 580nMAssay Description:Inhibition of Mycobacterium tuberculosis EthRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50462575(CHEMBL4238121)
Affinity DataKi:  29nMAssay Description:Inhibition of factor 10a (unknown origin) pre-incubated for 2 hrs before fluorescence substrate addition and measured after 5 mins by fluorescence as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional ligase/repressor BirA(Staphylococcus aureus)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM161470(US9108978, 4.01)
Affinity DataKi:  660nMAssay Description:Inhibition of Staphylococcus aureus biotin protein ligase by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)