Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50001272
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50088301((E)-N,N-dimethyl-N-(4-(2-p-tolyl-6,7-dihydro-5H-be...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274427(CHEMBL4128498)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274419(CHEMBL4130047)
Affinity DataIC50: 74nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274493(CHEMBL4126360)
Affinity DataIC50: 195nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274491(CHEMBL4130191)
Affinity DataIC50: 336nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274420(CHEMBL4127580)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274477(CHEMBL4128514)
Affinity DataIC50: 550nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274432(CHEMBL4127135)
Affinity DataIC50: 638nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274427(CHEMBL4128498)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of Rantes-induced intracellular Ca2+ ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274421(CHEMBL4128742)
Affinity DataIC50: 720nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274492(CHEMBL4128975)
Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274423(CHEMBL4127096)
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274422(CHEMBL4128487)
Affinity DataIC50: 1.61E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274481(CHEMBL4126779)
Affinity DataIC50: 1.73E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274480(CHEMBL4128015)
Affinity DataIC50: 1.82E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274418(CHEMBL4126032)
Affinity DataIC50: 2.47E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274431(CHEMBL4125768)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274490(CHEMBL4128832)
Affinity DataIC50: 2.97E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274433(CHEMBL4128372)
Affinity DataIC50: 3.86E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274424(CHEMBL4127249)
Affinity DataIC50: 4.45E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274479(CHEMBL4126634)
Affinity DataIC50: 4.94E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274478(CHEMBL4128399)
Affinity DataIC50: 5.05E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274434(CHEMBL4128658)
Affinity DataIC50: 7.83E+3nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274425(CHEMBL4125866)
Affinity DataIC50: 1.23E+4nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274426(CHEMBL4126007)
Affinity DataIC50: 1.94E+4nMAssay Description:Antagonist activity at CCR2 (unknown origin) expressed in CHOK1 cells co-expressing Ga16 assessed as inhibition of CCL2 induced intracellular Ca2+ mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274428(CHEMBL4127538)
Affinity DataKi:  2nMAssay Description:Binding affinity to human CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274429(CHEMBL4126162)
Affinity DataKi:  15nMAssay Description:Binding affinity to human CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50274430(CHEMBL4127496)
Affinity DataKi:  24nMAssay Description:Binding affinity to human CCR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/12/2020
Entry Details Article
PubMed