Compile Data Set for Download or QSAR
Report error Found 53 Enz. Inhib. hit(s) with all data for entry = 50001255
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273870(CHEMBL4126247)
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273805(CHEMBL4127623)
Affinity DataIC50: 20nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273886(CHEMBL4129012)
Affinity DataIC50: 22nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273809(CHEMBL4127804)
Affinity DataIC50: 23nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273869(CHEMBL4127964)
Affinity DataIC50: 25nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)
Affinity DataIC50: 28nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273831(CHEMBL4128143)
Affinity DataIC50: 28nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273900(CHEMBL4128261)
Affinity DataIC50: 30nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273872(CHEMBL4129575)
Affinity DataIC50: 32nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273901(CHEMBL4129431)
Affinity DataIC50: 33nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273843(CHEMBL4126768)
Affinity DataIC50: 36nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273846(CHEMBL4126984)
Affinity DataIC50: 41nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273871(CHEMBL4126126)
Affinity DataIC50: 42nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273797(CHEMBL4126304)
Affinity DataIC50: 46nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273798(CHEMBL4129046)
Affinity DataIC50: 50nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273807(CHEMBL4127608)
Affinity DataIC50: 51nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)
Affinity DataIC50: 54nMAssay Description:Inhibition of human FASN KR-domain after 20 mins in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273892(CHEMBL4127027)
Affinity DataIC50: 69nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273836(CHEMBL4129242)
Affinity DataIC50: 79nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273890(CHEMBL4129240)
Affinity DataIC50: 83nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273772(CHEMBL4126572)
Affinity DataIC50: 120nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273885(CHEMBL4128043)
Affinity DataIC50: 130nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM268608((R)-1-((1-(cyclopropanecarbonyl)pyrrolidin-3-yl)me...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM268883((4RS)-1-(((R)-1-(cyclopropanecarbonyl)pyrrolidin-3...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273868(CHEMBL4129199)
Affinity DataIC50: 160nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273842(CHEMBL4126910)
Affinity DataIC50: 170nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273888(CHEMBL4129812)
Affinity DataIC50: 200nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273893(CHEMBL4130300)
Affinity DataIC50: 250nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273796(CHEMBL4125929)
Affinity DataIC50: 300nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273889(CHEMBL4126387)
Affinity DataIC50: 300nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273832(CHEMBL4126662)
Affinity DataIC50: 300nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273845(CHEMBL4130264)
Affinity DataIC50: 360nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273835(CHEMBL4127999)
Affinity DataIC50: 450nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273775(CHEMBL4127363)
Affinity DataIC50: 460nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273887(CHEMBL4128858)
Affinity DataIC50: 460nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM269265((4RS)-1-(((R)-1-(Cyclopropanecarbonyl)pyrrolidin-3...)
Affinity DataIC50: 490nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273808(CHEMBL4130221)
Affinity DataIC50: 550nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273844(CHEMBL4127681)
Affinity DataIC50: 590nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273690(CHEMBL4130174)
Affinity DataIC50: 590nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273810(CHEMBL4125982)
Affinity DataIC50: 790nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273833(CHEMBL4126535)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273891(CHEMBL4129083)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273834(CHEMBL4125794)
Affinity DataIC50: 8.51E+3nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273884(CHEMBL4127223)
Affinity DataIC50: 8.71E+3nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273806(CHEMBL4128202)
Affinity DataIC50: 8.91E+3nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetFatty acid synthase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273811(CHEMBL4127845)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length FASN using [3H]-acetyl-CoA/malonyl-CoA as substrate after 60 mins in presence of NADPH by scintillation proximity ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50273812(CHEMBL4125752)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2020
Entry Details Article
PubMed
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