Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50002255
TargetLanosterol synthase(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50128065({4-[6-(Allyl-methyl-amino)-hexyloxy]-2-fluoro-phen...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50456340(CHEMBL4207987)
Affinity DataIC50: 16nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50456341(CHEMBL4212932)
Affinity DataIC50: 120nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
National Institute of Advanced Industrial Science and Technology (Aist)

Curated by ChEMBL
LigandPNGBDBM50456342(CHEMBL4210513)
Affinity DataIC50: 230nMAssay Description:Inhibition of human C-terminal His6-tagged OSC expressed in Pichia pastoris GS115 using 2,3-oxidosqualene as substrate after 90 mins by 1H NMR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed