Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50001840
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406031(CHEMBL4175045)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406179(CHEMBL4166609)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406175(CHEMBL4175782)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406184(CHEMBL4164396)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406036(CHEMBL4162767)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406183(CHEMBL4159404)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406176(CHEMBL4166210)
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406033(CHEMBL4173032)
Affinity DataIC50: 175nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406264(CHEMBL4173470)
Affinity DataIC50: 202nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406036(CHEMBL4162767)
Affinity DataIC50: 281nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406184(CHEMBL4164396)
Affinity DataIC50: 317nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406031(CHEMBL4175045)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406179(CHEMBL4166609)
Affinity DataIC50: 648nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406175(CHEMBL4175782)
Affinity DataIC50: 660nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406094(CHEMBL4165126)
Affinity DataIC50: 839nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406264(CHEMBL4173470)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406033(CHEMBL4173032)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406183(CHEMBL4159404)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406181(CHEMBL4174523)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406176(CHEMBL4166210)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406094(CHEMBL4165126)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406034(CHEMBL4176827)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406035(CHEMBL4170033)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 1 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406035(CHEMBL4170033)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406181(CHEMBL4174523)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50406034(CHEMBL4176827)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human GST-tagged EGFR T790M/L858R double mutant expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed