Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50001206
TargetAcid-sensing ion channel 1(Rat)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM50157090(6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of ASIC1a in rat dorsal root ganglion neurons assessed as reduction in peak current preincubated for 120 secs followed by acid medium stim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetAcid-sensing ion channel 1(Rat)
Anhui Medical University

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-N-carbamimidoyl-6-chloropyrazine-2-car...)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of ASIC1 in Sprague-Dawley rat articular chondrocytes assessed as decrease in acid-induced intracellular calcium level by Fluo-3AM dye bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)