Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50002436
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 10nMAssay Description:Inhibition of 20S proteasome activity in human ANBL-6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant GSTO1-1 incubated for 30 mins by fluorescence polarization based gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458515(CHEMBL1502738)
Affinity DataIC50: 28nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458516(CHEMBL4210652)
Affinity DataIC50: 31nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 35nMAssay Description:Inhibition of GSTO1-1 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458522(CHEMBL4203414)
Affinity DataIC50: 40nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by 4-NPG substrate based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase P(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458517(CHEMBL4216562)
Affinity DataIC50: 51nMAssay Description:Inhibition of human GSTP1-1 expressed in HEK293 cells by by CDNB-GSH conjugation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458520(CHEMBL1486332)
Affinity DataIC50: 54nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM54247(MLS000590567 | cid_3850682 | 2-chloro-N-[(3,4-dime...)
Affinity DataIC50: 120nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by 4-NPG substrate based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50277889(CHEMBL451887 | CARFILZOMIB)
Affinity DataIC50: 150nMAssay Description:Inhibition of GSTO1-1 (unknown origin) pre-incubated for 1 hr before GSH addition by CDNB-GSH conjugation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458514(CHEMBL4214871)
Affinity DataIC50: 400nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase P(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458513(CHEBI:18145 | Alpha Tocopherol | Aquasol E | E307 ...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human GSTP1-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM43766(SMR000156275 | 5,7-dihydroxy-2-(1-hydroxy-4-oxocyc...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by 4-NPG substrate based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458519(CHEMBL4211176)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human GSTO1-1 by MMA (V) reductase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458511((+)-ALPHA-TOCOPHERYL SUCCINATE | Alpha-Tocopheryl ...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human GSTO1-1 by MMA (V) reductase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50103597(CHEBI:77260 | Antra | H 168/68 | H-168/68 | Losec ...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458518(CHEMBL4211589)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of GSTO1-1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50186231([2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]ace...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human GSTO1-1 by MMA (V) reductase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50371232(CARNOSIC ACID)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by 4-NPG substrate based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50370232(BA-41166E | L-5103 | Rifadin | Rifampicin | RIFAMP...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of GSTO1-1 (unknown origin) by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458521(CHEBI:34718 | 1-chloro-2,4-dinitrobenzene | Dinitr...)
Affinity DataIC50: 9.00E+5nMAssay Description:Inhibition of human GSTO1-1 by MMA (V) reductase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM225702(CS331)
Affinity DataIC50: 1.02E+6nMAssay Description:Inhibition of human GSTO1-1 by MMA (V) reductase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed