Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50002232
TargetPyruvate kinase PKM(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50455475(CHEMBL1085588)
Affinity DataEC50:  92nMAssay Description:Activation of recombinant human PKM2 expressed in Escherichia coli BL21 at 4 uM incubated for 50 mins measured over 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50455476(CHEBI:6922 | Micheliolide)
Affinity DataEC50:  6nMAssay Description:Activation of recombinant human PKM2 expressed in Escherichia coli BL21 at 4 uM incubated for 50 mins measured over 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPyruvate kinase PKM(Human)
Nankai University

Curated by ChEMBL
LigandPNGBDBM50455474(CHEMBL4218770)
Affinity DataKi:  50nMAssay Description:Irreversible binding affinity to recombinant human PKM2 expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed