Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50002063
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 310nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetDNA gyrase A/A/B/B tetramer(Escherichia coli (strain K12))
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452869(CHEMBL4206009)
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of Escherichia coli DNA gyrase A2B2 using relaxed pNO1 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50452870(CHEMBL4203118)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated midazolam metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452872(CHEMBL4210894)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG transfected in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sanofi R&D

Curated by ChEMBL
LigandPNGBDBM50452871(CHEMBL4218256)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4-mediated testosterone metabolism in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed