Compile Data Set for Download or QSAR
Report error Found 86 Enz. Inhib. hit(s) with all data for entry = 50013239
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294427(US9586959, Compound disclosed in WO 2010030785, Ex...)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50: 27nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294418(US9586959, Compound 96)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at recombinant human histamine H4 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine induced st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM22566(CHEMBL129198 | 5-chloro-2-[(4-methylpiperazin-1-yl...)
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294386(US9586959, Compound 49)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294377(US9586959, Compound 29)
Affinity DataIC50: 52nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294415(US9586959, Compound 93)
Affinity DataIC50: 53nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294361(US9586959, Compound 4)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]BRL 43694 from human recombinant 5-HT3 receptor after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294416(US9586959, Compound 94)
Affinity DataIC50: 62nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294368(US9586959, Compound 18)
Affinity DataIC50: 65nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294364(US9586959, Compound 12)
Affinity DataIC50: 67nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294361(US9586959, Compound 4)
Affinity DataIC50: 77nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294362(US9586959, Compound 7)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563967(CHEMBL4798729)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294380(US9586959, Compound 35)
Affinity DataIC50: 170nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294367(US9586959, Compound 17)
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294398(US9586959, Compound 64)
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563970(CHEMBL4793425)
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563971(CHEMBL4784683)
Affinity DataIC50: 270nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294390(US9586959, Compound 53)
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50: 290nMAssay Description:Displacement of [3H]-histamine from recombinant mouse histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294401(US9586959, Compound 66)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294370(US9586959, Compound 20)
Affinity DataIC50: 380nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294411(US9586959, Compound 78)
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294410(US9586959, Compound 77)
Affinity DataIC50: 490nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294360(US9586959, Compound 2)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294372(US9586959, Compound 23)
Affinity DataIC50: 520nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563968(CHEMBL4776004)
Affinity DataIC50: 570nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50: 690nMAssay Description:Antagonist activity at recombinant mouse histamine H4 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine induced st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294369(US9586959, Compound 19)
Affinity DataIC50: 760nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294442(US9586959, Compound 36)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294461(US9586959, Compound 84)
Affinity DataIC50: 1.20E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50015795(CHEMBL306316 | 4-(4-Methyl-piperazin-1-yl)-[1,2,4]...)
Affinity DataIC50: 2.30E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563972(CHEMBL4796300)
Affinity DataIC50: 2.90E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294431(US9586959, Compound 6)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294429(US9586959, Compound 3)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294434(US9586959, Compound 10)
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294427(US9586959, Compound disclosed in WO 2010030785, Ex...)
Affinity DataIC50: 4.40E+3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294433(US9586959, Compound 9)
Affinity DataIC50: 4.80E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294432(US9586959, Compound 8)
Affinity DataIC50: 5.20E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563969(CHEMBL4790726)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294440(US9586959, Compound 30)
Affinity DataIC50: 6.30E+3nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294459(US9586959, Compound 82)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294457(US9586959, Compound 79)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294456(US9586959, Compound 76)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-histamine from recombinant human histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563972(CHEMBL4796300)
Affinity DataIC50: 1.10E+4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM50563968(CHEMBL4776004)
Affinity DataIC50: 1.50E+4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294377(US9586959, Compound 29)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Sungkyunkwan University

Curated by ChEMBL
LigandPNGBDBM294401(US9586959, Compound 66)
Affinity DataIC50: 2.40E+4nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in CHO-K1 cell membranes measured after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
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