Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50000897
TargetMelanocortin receptor 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50:  2.20E+4nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263381(CHEMBL4097903)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263393(CHEMBL4072638)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263393(CHEMBL4072638)
Affinity DataEC50:  4.50E+3nMAssay Description:Displacement of Eu-NDP-MSH from human MC1R expressed in HEK293T cells after 2 hrs by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.410nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.870nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.330nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263383(CHEMBL4079142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263381(CHEMBL4097903)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263393(CHEMBL4072638)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263381(CHEMBL4097903)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50:  3.80E+3nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.130nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263383(CHEMBL4079142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50:  1.40E+3nMAssay Description:Displacement of Eu-NDP-MSH from human MC1R expressed in HEK293T cells after 2 hrs by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.0700nMAssay Description:Displacement of Eu-NDP-MSH from human MC1R expressed in HEK293T cells after 2 hrs by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263383(CHEMBL4079142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50:  5.20E+3nMAssay Description:Agonist activity at mouse MC5R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263383(CHEMBL4079142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263393(CHEMBL4072638)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC4R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263383(CHEMBL4079142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50:  1.40E+4nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263393(CHEMBL4072638)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC3R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263383(CHEMBL4079142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263382(CHEMBL4065418)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Mouse)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50017181(CHEMBL441738)
Affinity DataEC50:  0.0400nMAssay Description:Agonist activity at mouse MC1R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263381(CHEMBL4097903)
Affinity DataEC50:  7.40E+3nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as increase in cAMP production incubated for 2 hrs by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263381(CHEMBL4097903)
Affinity DataIC50: 2.60E+4nMAssay Description:Displacement of [125I]-NDP-MSH from human MC1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50263381(CHEMBL4097903)
Affinity DataKi:  30nMAssay Description:Displacement of Eu-NDP-MSH from human MC1R expressed in HEK293T cells after 2 hrs by DELFIA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details Article
PubMed